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Publications Accepting the Challenge

Accepting The Challenge was published on behalf of the SRWC by Stream Restoration Incorporated in 2001. The purpose of the book is to provide an overview for the general public about the history, cause, and solutions to abandoned mine drainage. The book was written by Will Taylor, of the Jennings Environmental Education Center. The book is an excellent teacher resource, covering the history and techniques of coal mining as well as the impact it has on our land and water. We hope you will take the time to learn more about abandoned mine drainage and its effects on our watersheds.

Accepting The Challenge

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Wil Taylor is an active participant of the Slippery Rock Watershed Coalition and is currently the Park Manager at the Jennings Environmental Education Center. Jennings is a resource-based state park located near the town of Slippery Rock, in Butler County that features the only protected and managed prairie in Pennsylvania, several endangered plants and animals and an abandoned mine that discharges severely degraded mine drainage which is being treated by a environmentally-friendly passive treatment system. Wil has developed and facilitated many educational and interpretive programs centered around the history of the mine, the issue of abandoned mine drainage and passive treatment. These programs have included teacher workshops, agency trainings, college courses, middle school and high school programs and community events and presentations. After teaching about coal mining and abandoned mine drainage for a number of years, Wil decided that it would be beneficial to the general public to write a book about history, cause, and solutions to abandoned mine drainage. The book “Accepting the Challenged” was first published in 2001 by Stream Restoration Incorporated.

Wil Taylor

Accepting The Challenge is not only a wonderful book for an individual wishing to learn on their own, but it is also an excellent reference and teaching tool for teachers from elementary school through college. The book brings together many different areas of study including history, geology, chemistry, biology, environmental science, and engineering. The book is easy to read and has some interesting historic pictures. In addition, the digital version provides numerous links to additional content available on the web including videos, books, scientific papers, teaching resources and organizational websites containing more resources and links, which will allow the interested reader to further explore the various topics covered in the book.

In order to write and publish Accepting the Challenge, the Slippery Rock Watershed Coalition enlisted the assistance of many in the public and private sector. This public/private partnership is an excellent example of what can be accomplished when a variety of people and organizations work together to accomplish a common goal. We would like to extend our sincere appreciation to the companies, agencies, and individuals that made this publication possible.

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Monographs

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The NAS Monograph Series is the vehicle for the publication of rather more substantial pieces of work than a paper for IJNA or another academic journal. The series is a joint imprint with Archaeopress, publishers of the BAR series.

A monograph is devoted to the publication of a specific piece of research in the field of nautical archaeology and presents final excavation results, rather than interim findings.

The series provides the opportunity for the publication of NAS Part II/ IV reports and appropriate Master's and Doctoral theses and dissertations, together with other material submitted by members of the NAS. It also offers the opportunity for the publication of appropriate reports by licensees. NAS Monographs

The Oru and the Yatra The Oru and the Yatra monograph published in 1992 and written by Vini Vitharana, was the first extended study of the traditional Sinhalese outrigger logboat and is available online. Simply click here.

With the devastation of Sri Lanka’s shoreline in the 2004 tsunami, the country’s traditional watercraft were decimated. Although these vessels still fulfil the same function as they have in the past, traditional building methods are fast being abandoned.

The Forton Lake Archaeology Project NAS Monograph 3 The Forton Lake Archaeology Project carried out between 2006 and 2009 by the Nautical Archaeology Society and the Hampshire and Wight Trust for Maritime Archaeology (HWTMA), investigated the remains of the hulks vessels and the associated history of the Forton Lake area in Gosport, Hampshire, UK.

This monograph is written by Mark Beattie-Edwards and Julie Satchel, with contributions by Jane Maddocks, Alison James, Mary Harvey, Julian Whitewright, Daniel Pascoe and Paul Donohue.

Records of Traditional Watercraft from South and West Sri Lanka The second of the NAS monograph series is a record by Gerhard Kapitän in pictures and scale drawings of the fast disappearing traditional watercraft of Sri Lanka.

The Sound of Mull Project The first monograph in the series, Philip Robertson's The Sound of Mull Archaeological Project (SOMAP), 1994-2005, with contributions from Jane Maddocks and Steve Webster,is an account of the work carried out over a decade by volunteer divers under the auspices of the NAS recording the investigation of a number of wrecks lying in this historically important waterway off the west coast of Scotland. It comes with an interactive CD-ROM.

Orders Copies of NAS monographs may be ordered from the NAS shop.

Editor Authors seeking to publish in the monograph series are invited to contact the series editor:

Dr Julian Whitewright, C/O NAS, Fort Cumberland, Eastney, Portsmouth, PO4 9LD. Email: nas@nauticalarchaeologysociety.org

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1998. The effect of treatment with alpha-interferon on hepatitis G GBV-C viraemia SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY , 33 (2), pp. 195-200. | Ted Baker Womens / Serenity Giellip Trainers Buy Cheap Best Free Shipping Latest Collections Under 70 Dollars fKupy
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Background. Hepatitis G virus (HGV) or GBV-C is frequently detected in patients co-infected with hepatitis C virus (HCV). This study investigated host and virologic factors influencing the response to HGV/GBV-C to α-interferon treatment. Methods: HGV/GBV-C was detected and quantified by nested polymerase chain reaction. The influence of variables such as liver biopsy appearance, liver function abnormalities, and response of HCV to interferon treatment was monitored. Results: Fourteen of the 25 HGV/GBV-C-infected patients treated with interferon (3-6 MIU three times a week for 6 months) became non-viraemic during treatment, although all relapsed after treatment withdrawal at 6 months, with no net change in virus load between 0 and 12 months. Conclusions: Predictive factors for clearance of HGV/GBV-C viraemia by interferon were pre-treatment severity of liver disease (median Knodell score of 4, compared with 7 for non-responders; P = 0.030) and alanine aminotransferase levels (median, 114, 182 for non-responders; P = 0.039). Clearance was associated with the treatment response of HCV. Nine of 13 who cleared HGV/GBV-C also cleared HCV, compared with 3 of 11 HGV/GBV-C non-responders; P= 0.05). The shared susceptibility of HGV/GBV-C and HCV to interferon treatment suggests a link between the mechanism of clearance of the two viruses.

Jarvis LM , Bell H , Simmonds P , Hawkins A , Hellum K , Harthug S , Maeland A , Ritland S , Myrvang B , von der Lippe B , Raknerud N , Skaug K et al . 1998. The effect of treatment with alpha-interferon on hepatitis G/GBV-C viraemia. The CONSTRUCT Group. Scand J Gastroenterol , 33 (2), pp. 195-200. | Clarks Tri Amber Womens Sneakers Finishline Cheap Price Cheap Discount Sale Clearance Footlocker Pictures rfOqobL

BACKGROUND: Hepatitis G virus (HGV) or GBV-C is frequently detected in patients co-infected with hepatitis C virus (HCV). This study investigated host and virologic factors influencing the response to HGV/GBV-C to alpha-interferon treatment. METHODS: HGV/GBV-C was detected and quantified by nested polymerase chain reaction. The influence of variables such as liver biopsy appearance, liver function abnormalities, and response of HCV to interferon treatment was monitored. RESULTS: Fourteen of the 25 HGV/GBV-C-infected patients treated with interferon (3-6 MIU three times a week for 6 months) became non-viraemic during treatment, although all relapsed after treatment withdrawal at 6 months, with no net change in virus load between 0 and 12 months. CONCLUSIONS: Predictive factors for clearance of HGV/GBV-C viraemia by interferon were pre-treatment severity of liver disease (median Knodell score of 4, compared with 7 for non-responders; P = 0.030) and alanine aminotransferase levels (median, 114, 182 for non-responders; P = 0.039). Clearance was associated with the treatment response of HCV. Nine of 13 who cleared HGV/GBV-C also cleared HCV, compared with 3 of 11 HGV/GBV-C non-responders; P = 0.05). The shared susceptibility of HGV/GBV-C and HCV to interferon treatment suggests a link between the mechanism of clearance of the two viruses.

Strappe PM , Wang TH , McKenzie CA , Lowrie S , Simmonds P , Bell JE . 1998. In situ polymerase chain reaction amplification of HIV-1 DNA in brain tissue. J Virol Methods , 70 (2), pp. 119-127. | Moschino Flat Sandals Shoes Women Couture 100% Authentic Fashionable Sale Online Factory Outlet ROfr31ZT
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A direct in situ polymerase chain reaction (IS-PCR) assay is described for the detection of HIV-1 proviral DNA in formalin fixed paraffin embedded brain tissue. Biotin-16-dUTP is incorporated during the PCR process and microwave pretreatment of tissue sections ensures that no non-specific incorporation into damaged or nicked genomic DNA occurs. Two methods are compared to detect the biotinylated amplified product, the use of an avidin-biotin-alkaline phosphatase complex (ABC) and the application of tyramide signal amplification (TSA) which allows both chromogenic and fluorescence detection. TSA detection enhances the sensitivity of IS-PCR, permitting fewer PCR cycles and preserving tissue morphology.

Hanley JP , Jarvis LM , Hayes PC , Lee AJ , Simmonds P , Ludlam CA . 1998. Patterns of hepatitis G viraemia and liver disease in haemophiliacs previously exposed to non-virus inactivated coagulation factor concentrates. Thromb Haemost , 79 (2), pp. 291-295. | Show Abstract

Hepatitis G virus (HGV), a novel flavivirus, has been implicated as a cause of posttransfusion hepatitis. We have performed a longitudinal study in a cohort of haemophiliacs (n = 68) who previously received non-virus inactivated coagulation factor concentrates to assess both patterns of HGV viraemia and any associated liver disease. Hepatitis C virus (HCV) RNA was present in 58/68 and co-infection with human immunodeficiency virus (HIV) was present in 15/68. HGV RNA was detected in 17/68 (25%) samples from the mid-1980s. There was no association between either HIV infection (p = 0.74) or co-infection with a particular HCV genotype (p = 0.62). However, there was a relationship between HGV viraemia and the severity of haemophilia (p = 0.0004) with HGV RNA detected in 5/19, 9/16 and 3/32 patients with mild, moderate and severe haemophilia respectively. A longitudinal study was performed in 15/17 haemophiliacs with HGV viraemia using stored serum samples from the 1980s and 1990s. HGV viraemia persisted in 8/15 and cleared in 7/15 over a variable period of time. A Weibull model was constructed to estimate the duration of HGV viraemia in the study group. The 75th and 90th percentiles for the duration of HGV were estimated to be 8.7 years (95%, confidence interval 4.8-15.7) and 23.6 years (95% confidence interval 11.8-47.1) respectively. Laparoscopic liver inspection/biopsy was performed in 25/68. There was no association between severity of liver disease and HGV viraemia (p = 0.43). This study demonstrates considerable variation in patterns of HGV viraemia in haemophiliacs. We found little evidence to implicate HGV as a major cause of chronic liver disease in haemophiliacs.

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Poovorawan Y , Theamboonlers A , Chongsrisawat V , Seksarn P , Jarvis L , Simmonds P . 1998. High prevalence of hepatitis G virus infection in multiply transfused children with thalassaemia. J Gastroenterol Hepatol , 13 (3), pp. 253-256. | Show Abstract | Read more

We investigated the prevalence of hepatitis G virus (HGV) RNA in relation to the frequency of blood transfusions in thalassaemic children and in volunteer blood donors in Thailand. Furthermore, we studied the frequency of coinfection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV) as well as a possible relationship to the alanine aminotransferase (ALT) status of the blood samples, taken at random from thalassaemic children who have received multiple blood transfusions and from volunteer blood donors. The results show detectable HGV-RNA in 32.6% of transfusion patients and in 5% of blood donors. The prevalence of HGV-RNA peaked between the 11th and 50th transfusion. The relationship between HGV infection and ALT status was not statistically relevant.

Citation information in Europe Pubmed Central

The role of the third variable domain (V3) of gp120 in the neutralization of primary and T-cell line adapted (TCLA) strains of human immunodeficiency virus type 1 (HIV-1) by serum from HIV-1-infected individuals was investigated. A primary virus isolate, M2424/4, when adapted to H9 cells, was more sensitive to neutralization on MT2 cells than the same stock passaged in PBMC. Neutralization of the PBMC-passaged stock by V3-specific MAbs was abrogated by addition of V3 (MN) peptide. However, exogenous V3 (MN) peptide failed to reduce the neutralization of this isolate on PBMC, or MT2 cells, by high titre anti-HIV-1 polyclonal human sera in contrast to the extensive reduction of neutralization by the same sera on MT2 cells using the prototype MN strain (4- to > or = 24-fold) and the TCLA M2424/H9 isolate (2- to 8-fold). These results indicate that the neutralization of primary virus isolates by serum from HIV-1-infected individuals is not significantly mediated by V3-specific antibodies.

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